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  CHRONIC PROSTATITIS

First, it must be clearly understood that the term "prostate trouble" so commonly used is misleading. Many different things happen to the prostate gland including infection (acute and chronic prostatitis), enlargement, and nonspecific prostate pain and swelling. Enlargement can be due to a benign (or noncancerous) growth known as benign prostate hypertrophy, also called benign hyperplasia or B.P.H. Or, it can be due to cancer of the prostate which is also termed malignancy of the prostate gland.

While chronic prostatitis, with which we are dealing here, sometimes produces mild to moderate enlargement as a result of inflammation, this enlargement is only temporary and has no direct relationship to the permanent slowly progressive benign enlargement which occurs with age. Chronic prostatitis is more commonly seen in younger man, particularly between the ages of 30 to 50. However, it can and does occur in all ages from puberty on.

The term "prostate trouble" encompasses all of these conditions, but it is imperative that the patient does not get the idea that because he has chronic prostatitis, he will need surgery for "blocked kidneys" caused by benign hypertrophy, or that he has or will have anything as serious as cancer of the prostate. As a matter of fact, cancer of the prostate rarely occurs in an individual who suffers with chronic prostatitis.

General

Chronic prostatitis is extremely common. Many urologists feel that from 60 to 80% of men are afflicted to some degree. It may be present for many years without producing symptoms and finally become troublesome. The condition can and does occasionally result in rather severe symptoms but generally it is more of a nuisance than anything. It may be compared to chronic sinus trouble that will come and go. It may require regular treatment for months, even years on end, or it may respond favorably to one or two visits to the doctor. While chronic prostatitis may cause recurrent infections and may never really be "cured", the patient may be completely free of symptoms for weeks, months or years.

It is important to realize most doctors feel that elimination of symptoms of this condition is their principal aim, particularly since the prostate rarely returns to its normal state for any length of time regardless of how much it is treated.

The patient should not be discouraged in learning these things. Treatment will usually give him relief of his symptoms - often it will not be long before he realizes his improvement. However, as in any other problem, improvement can be slow and at times almost imperceptible.

Whenever improvement is delayed or very slow and frequent flareups of symptoms occur even the most patient patient becomes discouraged and depressed. Those who are not inclined toward patience will often become extremely dissatisfied with their progress, often with their physician.

Should the reader be of this nature, it is well for him to heed these words carefully and be reassured as patience will pay off if he can develop it. If not, he is doomed to continued and everlasting troubles as his physical disease will be complicated and exaggerated by anxiety. This type of individual goes from doctor to doctor and clinic to clinic seeking help, never giving one doctor a chance to afford the patient any appreciable relief.

Fortunately, these individuals are finally convinced, but only after repeated costly investigations and treatments by various doctors, that they should stay with one qualified, competent doctor until they realize results. Rarely this may take years, not infrequently months, but improvement will show itself in time. "Stay with it and have patience" is the only answer. Once improvement, if only slight, is noted, anxiety and nervous tension will decrease and symptoms will abate markedly.

To the majority of patients who will respond rapidly, a word of reassurance. Do not let the foregoing depress you. Difficult cases are unusual.

Cause of Chronic Prostatitis

The first question always asked of the doctor once he has announced the diagnosis to the patient is, "What causes it?" This will be answered by translating medical terminology into "plain English", for a background of anatomy, physiology and some understanding of bacteriology and disease processes is necessary to completely understand this condition.

We shall start with a brief course in anatomy to be followed with a few words regarding what happens to the anatomy of the prostate when it becomes chronically infected. The reader must understand that the writer is reducing a vast amount of information and detail to an oversimplified picture for our purposes here.

The prostate is located at the neck of the bladder. In fact, it might best be described as being incorporated into and surrounding the neck of the bladder. As the bladder neck joins the urethra (or tube we pass urine through) the prostate forms this area, and the ducts or drainage tubes of this gland empty into the urethral channel. Into the same area (and closely related) empty the ejaculatory ducts or channels through which semen passes after it leaves the seminal vesicles.

Since the seminal vesicles, the ejaculatory ducts, and the prostate are so closely related, chronic prostatitis also involves the seminal vesicles in many instances. The ejaculatory ducts pass through the prostate on their way to the urethra.

The prostate is made up of glandular tissue interlaced by and completely encapsulated by a fibrous capsule. This means the prostate gland is made up of "meat" resembling liver with a tough skin or shell which holds this soft gland tissue together and also separates it from surrounding anatomy If one can picture a small apple with the core removed being fastened to a neck of a bottle and the cored out apple serving as the bottle neck he will have a general idea of the relationship of the prostate to the bladder.

It will be noted that the prostate and bladder neck lie just in front of the rectum about 2-3 inches above the anus (outlet of the rectum). In fact, there is but one thin layer of fascia (fibrous tissue) between the prostatic capsule and the rectal tube. For this reason the doctor can easily examine the prostate gland by inserting a finger into the rectum. He can determine the size, the shape, the mobility, and the consistency of the gland this way.

All these things are important in making a diagnosis of prostate trouble and frequently a simple palpation is the only diagnostic test necessary. On other occasions, further tests are indicated to corroborate the impression received by rectal palpation but a vast amount of information is obtained by this simple, albeit admittedly annoying, examination.

So much for the gross anatomy and anatomical relations of the prostate gland. Now for the microscopic make-up of this organ.

There are a number of "sacks" which have tiny tubes leading to them. These sacks are like tiny microscopic "bottles" of living tissue which are lined with cells which secrete fluid. The fluid passes out the tubes or ducts which join other similar ducts, these groups of ducts joining other larger ducts until the main prostatic ducts empty the combined production of all these millions of tiny glands into the urethra.

If one compared this architecture with that of a bunch of grapes (glands) and the stems (ducts) all joining to form one main stem (duct), he would have a similar arrangement. Yet, he must remember the entire prostate gland is made up of billions of these very tiny glands and their ducts and that they are so tiny as to be visualized only by the high magnification of a microscope.

Understanding the microscopic architecture of the prostate with the realization that this vast system of billions of tiny "sacks" of fluid drain into a network of ducts which are tributaries of more ducts which again join and join again to finally empty into the urethra through 14-18 main ducts leads us to an understanding of the problems that develop when infection (bacterial invasion) occurs. The cause of prostatitis is infection; however, this answer does not suit the average patient - he wants to know more. Hence the foregoing details.

Whenever infection, irritation or allergy involves the prostate gland, inflammation results. Inflammation results in edema (swelling), an easily understandable process so far. The usual course of events whenever this occurs in other parts of the body is that inflammation and swelling gradually subside as the resistance of the body and medication combat the infection or irritation. The problem in the prostate (and some other parts of the body with similar drainage systems) is different, however. The duct linings swell also, occluding or partially occluding the ducts. Infected or irritated fluid is retained in millions of tiny microscopic sacs or glands.

Whenever drainage of a closed or partially closed space is restricted, inflammation get a deeper foothold. In this case, it extends through the walls of the glands and finally enters the spaces and tissues between these glands. When this happens, the process is, practically speaking, irreversible inspite of large amounts of medication and treatment. Whether the initial pathogen invasion is abrupt or overwhelming as in acute prostatitis, or whether it is gradual, the end result is chronic prostatitis and most likely will end up as a permanent condition. In short, the case of chronic prostatitis is pathogen invasion or inflammation and it becomes chronic because the inflammation has obtained a foothold in closed or partially closed spaces and crevices of glandular tissue.

What to do for chronic prostatitis ahs always been a problem for physicians and whenever a condition is problematical, many different methods of treatment will be available. Through the years innumerable ways of treatment have been tried with also many variations of these treatments. Treatment - the amount and the extent of it - will depend on each individual patient and the preferences of the individual doctor who renders treatment.

Nonspecific treatment may be of help in allaying symptoms of prostatitis, such as a hot tub of warm or hot water for 30 minutes daily to allow the heat to improve circulation to the prostate region and allow the body defenses to help fight the inflammation. Diet adjustment may be necessary, as certain individuals are sensitive to caffeine-containing liquids, alcohol, or specific nutrients. A diary checklist may help identify an allergy-causing food. Prostatic massage may be of help in milking out all of the secretions in the ducts and glands. Massage is carried out by a physician stroking the prostate with a finger inserted in the rectum. A pleasant alternative to this massage is regular intercourse by which the prostatic ducts and glands are emptied. Through the analysis of the expressed secretions during a rectal exam, a specific drug therapy may be advised. Unfortunately, each time a new medication is tried, improvement may result temporarily, but recurrences can often result as the infecting organism becomes used to the drug therapy.

Other forms of pharmacological medications may be tried to decrease swelling and inflammation and they have been used with various degrees of success. Such medications as anti-edema, anti-inflammatory, muscle relaxant, and hormones have been used. Vitamins and mineral supplements may also be helpful in certain selected individuals.

Treatment of chronic disorders in organs surrounding the prostate and sharing a common drainage with the prostate may be beneficial. Correction of chronic constipation and treatment of colitis, diverticulitis, and rectal problems are examples. An excellent form of therapy that is not pharmacological is reassurance. Some individuals are unnecessarily preoccupied with their symptoms, leading to a stress that will further aggravate these symptoms. Assurance that chronic prostatitis is not a critical disease, that it will not lead to impotence, sterility, or cancer, and that these individuals can live a normal lifestyle with normal sexual habits is of help to many anxious males. Each individual with chronic prostatitis should review his own lifestyle habits to see if there is any pattern leading to recurrence of his symptoms.

The patient should not expect results too soon. He may notice immediate improvement but should certainly not be disappointed or discouraged if it takes weeks or even months. This has been emphasized before but it pays to repeat it.

Probably the next question asked of the physician is, "How does the infection get there?" Prior to the advent of the miracle antibiotics, gonorrhea or "clapp" used to be a favorite causative organism. Now, prostatitis can be caused by a variety of pathogens, varying from bacteria, Chlamydia, Myoplasmum, Trichomonas, or no pathogens at all. The organisms can reach the prostate via the blood or lymph stream, or through the urethra directly. A focus of infection elsewhere in the body can be a contributing factor. Many, many times we never know how the infection reaches the prostate.

We will now say a few more things about treatment. Then we will discuss symptoms and signs and also further diagnostic tests for the patient who wishes to learn more details regarding chronic prostatitis.

In passing, we mentioned that the seminal vesicles are frequently involved and it might be mentioned here that prostatic massage usually includes massage of the seminal vesicles and the results are the same.

While surgery is not recommended by most authorities because they feel that the results are apt to be detrimental rather than beneficial, there are cases in which surgery is beneficial to a great degree.

These are the cases in which there is also benign enlargement of the prostate as well as chronic infection of the gland, thus producing some retention of urine in the bladder. In cases of this nature the retained (or residual) urine in the bladder stagnates and becomes another place for infection to be harbored and propagated. Removal or partial removal of the prostate by surgery will definitely help in a case like this as it is necessary for the bladder to empty freely if the prostate is infected.

Surgery will also help in some cases in which the infection of the prostate is due to stones in the prostate gland. These occasionally occur and are known as prostatic calculi. They produce a foreign body effect - that is, infection.

The writer has frequently been asked, "Why not remove the prostate and get this over with?" This question usually comes from a longtime sufferer who is ready to undergo surgery or anything else to get over it completely. While the prostate is not at all necessary to a comfortable, normal (in every way) life, surgery for chronic prostatitis is simply not feasible for the reasons stated previously.

One hears of prostate glands being removed frequently and they are. However, this is done in cases of enlargement due to age and the capsule is not removed in any of the different types of commonly used operations. There is one exception and this will be discussed shortly.

The commonly used operations or approaches to removal of an enlarged prostate all leave the capsule and a layer of prostatic tissue. This means that some infected tissue would remain and in chronic prostatitis little would be accomplished. Thus to remove the capsule as well, a vastly more radical and complicated procedure is necessary - in fact, a procedure which can result in incontinence of urine and/or impotence. Thus the reasons for not recommending surgery should be clear. This brings us to the exceptions mentioned above. The entire gland, capsule, seminal vesicles, bladder neck, etc., are removed by radical surgery in cases of early cancer of the prostate.

Symptoms and Signs

Fortunately no one has all the symptoms that can result from chronic prostatitis. Usually, the patient will suffer from one or two of them but many have quite a number more, particularly if their case is severe.

In the writer's experience the most common complaint that brings the patient to the doctor is pain in the testicles - usually mild. He may complain of pain in both inguinal regions (or one side only), these being either side of the groin. He may have moderate or mild pain in both inguinal regions radiating into the testicles (again it may be one side only)

Low backache is a very common complaint and this is often relieved immediately by one treatment. Other symptoms include burning on urination, frequency of urination, increases sexual desires, lack of or reduced sexual desires, slight discharge from urethra, premature ejaculation, painful ejaculation, backache following intercourse. Any combination of the foregoing may exist and to any degree of severity. Rarely there will be pain felt in the urethra just behind the head of the penis. This is what is known as "referred pain" and has its origin in the prostate or in the posterior urethra where the prostatic ducts empty. Sometimes these patients are hard to convince that their discomfort originates from higher up.

Now as regards "signs" of chronic prostatitis. Some signs may lead to the discovery of the disease even though the patient has not had any symptoms or discomfort. This may occur during a routine physical exam. Pus or blood cells or both may be discovered in the urine by the doctor. He may also discover a ascertain consistency of the prostate by routine rectal examination and tests. The gland may feel soft or "boggy". Other changes in the consistency may also indicate it. Massage may produce prostatic secretion with more than a normal number of white (pus) cells when examined under the microscope.

Occasional seminal fluid will be noticeably bloody. This is a sign of infection of the posterior urethra into which the prostatic ducts drain infected irritating secretion. Often another symptom manifested by pain in the area between thighs just behind the scrotum is due to posterior urethritis.

It should be mentioned at this point that very rarely mild cases of chronic prostatitis can be very easily missed, as a considerable amount of infection may not produce any changes in the consistency of the gland or any symptoms. A point is made of this because a routine examination by a completely able doctor may miss it and a week later or years later, the disease may be discovered by some other physician.

The principal diagnostic sign is the consistency of the gland by rectal palpation and the presence of numerous pus cells in the secretion. Examination of the expressed prostate secretion by chemical, microscopic and culture means is of excellent help in making the diagnosis. Occasionally, further studies are indicated including x-rays of the entire urinary tract and possibly cystoscopic examination. For example, pus may be discovered in the urine, examination of the prostate may indicate prostatitis, but this can also be accomplished by inspection of other parts of the genitourinary system, including the kidneys. Only a thorough investigation will reveal this.

In summarizing, I would like to simply repeat: Chronic prostatitis is rarely cured. It is a recurrent inflammation of the prostate gland. It is not dangerous and it will in time respond to proper treatment. It will probably cause symptoms from time to time and is not apt to cause cancer of the prostate.

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